LifeArc and Metrion Biosciences extend partnership agreement to support LifeArc’s neuroscience small molecule drug discovery programme.

Metrion Biosciences Limited (Metrion), the specialist ion channel CRO and drug discovery company, and LifeArc, the UK medical research charity previously known as MRC Technology, today announced an extension of  their existing partnership, to support LifeArc’s neuroscience drug discovery programme.

Under the terms of the agreement Metrion will provide validated ion channel and electrophysiology-based assays and safety profiling services, and LifeArc will conduct medicinal chemistry aimed at identifying novel modulators of an undisclosed CNS ion channel target. In addition, Metrion will contribute translational research expertise to evaluate the activity of LifeArc compounds in human neuronal networks, Metrion will provide translational assay support by applying its extensive background knowledge in ion channel research, microelectrode array (MEA) technology, and access to its CiPA-compliant cardiac safety assays.

You can read the full press release here.

Metrion Biosciences is a specialist ion channel contract research organisation and drug discovery business located in the Cambridge (UK) bio cluster. Metrion provides customers with access to a highly qualified and experienced team of ion channel experts, plus a range of high quality ion channel assays on a fee-for-service or collaboration basis. Metrion Biosciences’ specialist ion channel service offering includes an industry leading panel of in vitro cardiac ion channel safety assays (including hERG screening) translational neuroscience and cardiac assays, phenotypic assays for neuroscience-based and cardiotoxicity testing, and a range of other ion channel screening services such as cell line development and optimisation.

Our assay platforms include fluorescence-based screening, QPatch 48 and Patchliner automated electrophysiology, conventional electrophysiology, microelectrode array and impedance-based technologies.

Metrion Biosciences can provide tailored assay development and validation, in-depth and highly informed data analysis and reporting solutions, experienced and effective project management, plus quality assured data packages.  Working closely with our collaborators Assay.Works and Concept Life Sciences we also offer an expert integrated drug discovery service.

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