Metrion Biosciences Brochures
Ion Channel and HTS Services
Specialist ion channel screening to accelerate early-stage screening and lead optimisation.
- Make well-informed decisions with our fully customised ion channel assays.
- Cost-efficient and timely high-throughput assays.
- Ready-to-go and customised cell line generation.
- Increase diversity and efficiencies in screening and target identification.
- Case Study: Multi-assay high-throughput repurposing screen for rare epilepsy mutation in KCNC1 gene.
Please contact us if you would like further information on our Ion Channel and HTS Services.
Cardiac Safety Screening Services
Reliably evaluate the proarrhythmic and cardiotoxic liabilities of your compounds.
- Non-GLP hERG screening to eliminate cardiac risk liability.
- Comprehensive in vitro proarrhythmia assay.
- hiPSC-derived cardiomyocyte model for early cardiac derisking.
- Evaluate the effect of compounds on action potentials recorded from hiPSC-derived cardiomyocytes using manual patch screening.
- Chronic cardiotoxicity assay: hiPSC-derived cardiomyocytes to measure the cardiotoxic potential of test compounds.
- High-quality, cost effective and rapid turnaround GLP testing against hERG.
Please contact us if you would like further information on our Cardiac Safety Screening Services.
Specialist Neuroscience Services
Highly specialised and tailored neuronal assays for pharmacological screening.
- Panel of models with increasing complexity and translational relevance.
- Range of assay methodologies for accurate and efficient evaluation of candidates.
- Pave the way for innovative treatments for lysosome-related disorders.
- CNS discovery: brain slice assay.
- Case study: Multi-assay high-throughput repurposing screen for rare epilepsy mutation in KCNC1 gene.
Please contact us if you would like further information on our Neuroscience Services.
Let’s work together
What are your specific ion channel and assay needs?
If you have any questions or would to like discuss your specific assay requirements, we will put you directly in touch with a member of our scientific team. Contact us today to discover more.