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Ion Channel Screening

Metrion are committed to delivering efficient and successful Ion Channel Screening expertise, promptly and accurately to meet your specific needs.

Our ion channel and drug discovery screening capabilities enables us to provide reliable, high-quality data to accelerate and validate your drug discovery programmes.

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Cardiac Safety Screening

Metrion offers a range of high quality Cardiac Safety Screening assays, including components of the Comprehensive in Vitro Proarrhythmia Assay (CiPA) initiative.

Metrion can evaluate the proarrhythmic and cardiotoxic liabilities of your compounds by assessing their effects against a comprehensive panel of cardiac ion channels.

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Neuroscience

Metrion offers a range of peripheral and central nervous system (CNS) neuronal assays utilising native rodent tissue and human iPSC-derived neurons.

Our Neuroscience assays are used for two main drug discovery purposes: Confirmation of compound effects in native neuronal systems and neurotoxicity screening.

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Translational Assays

Metrion offer a set of reliable and reproducible translational cell-based assays to demonstrate the efficacy, selectivity, and potency of your potential therapeutic candidate.

Our translational assays are used for two main drug discovery purposes: Cardiac assays and Neuroscience.

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Integrated Drug Discovery

Metrion’s know-how and breadth of services adds value to drug discovery programmes by developing and de-risking ion channel modulators as they progress towards nomination for clinical development.

Our experience will guide your drug discovery research programme successfully and cost effectively. We offer wide ranging expertise and pre-validated industry leading assays for ion channels.

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Let’s work together

What are your specific ion channel and assay needs?

If you have any questions or would like to discuss your specific assay requirements, we will put you directly in touch with a member of our scientific team. Contact us today to discover more.