Adam’s Journey into Electrophysiology

Written by Adam Young

My undergraduate qualifications

I completed my undergraduate degree with a BSc in Natural Sciences at the University of Bath in Summer 2021. I chose to major in pharmacology and minor in biology which was an excellent way to explore a breadth of different subjects, whilst also providing a depth of scientific understanding.

I particularly enjoyed studying various neuroscience units and learning about the intricate mechanisms underlying the physiological processes in the brain. I also developed an interest in the ways in which the brain can malfunction and how this can lead to a range of neurological diseases.

Adam Young
Adam Young, Metrion Biosciences

A placement at the Barrow Neurological Institute

During the third year of my degree, I was fortunate enough to be able to complete a placement year at the Barrow Neurological Institute in Phoenix, Arizona, where I joined the Whitaker-Lukas lab. I investigated the effects of the modulatory prototoxin, lynx1, on a subtype of nicotinic acetylcholine receptors as part of a project studying nicotine addiction. Through the year, I developed the technique of two-electrode voltage-clamp electrophysiology and thoroughly enjoyed this process! Not only did this experience expand my molecular biology skillset at the bench, but it also helped me to develop an appreciation for the elaborate nature of ion channel function within the brain. It was also an incredible opportunity to live in and explore another part of the world, and I am still very grateful for the experience!

My work so far at Metrion Biosciences

After completing my placement, I was particularly intrigued by the clinical potential of ion channels, particularly in neurological disorders. After graduating, I knew I wanted to continue to develop my knowledge of ion channels – as well as expand my abilities at the bench. I recently joined Metrion Biosciences exactly for these reasons and I am grateful for the opportunity to develop skills within manual and automated patch clamp electrophysiology. There are many fascinating ongoing drug development projects, and I am enjoying the challenge of making recordings from various ion channels. I look forward to continuing to develop within this role and contribute to various projects across the company.

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